Mesterolone has been used for physique- and performance-enhancing purposes by competitive athletes , bodybuilders , and powerlifters. Proviron is known to be manufactured by some well-known underground labs, while lesser known or smaller UGLs may not manufacture it due to the fact that it is nowhere near as popular as other products or ancillaries out there. Mesterolone was discovered and introduced for medical use in
Proviron Chemical Characteristics
Being that Proviron is not an anabolic steroid and possesses extremely weak anabolic effects, it is not utilized in the form of cycles. Hargreave 6 December Women are also prone to virilization through the use of Proviron, which is the development of male characteristics in females i. Mesterolone is marketed mainly under the brand name Proviron. In fact, as previously mentioned, Proviron acts as an anti-estrogen via its activity as an aromatase inhibitor in the body. Proviron is a modified derivative of dihydrotestosterone DHT via the addition of a methyl group on its first carbon 1-methyl dihydrotestosterone. National Association of Retail Druggists.
Research has demonstrated that because of this effect of Proviron, it has been utilized medically in the treatment of gynecomastia and breast cancers because of its strong androgenic nature combined with its anti-estrogenic capabilities.
Because Proviron is primarily an androgen, it does carry with it the risk of androgenic side effects, and they are more pronounced with higher dosages. Women are also prone to virilization through the use of Proviron, which is the development of male characteristics in females i. Because Proviron is not C alpha alkylated it is instead methylated on its first carbon , research has shown that it is not known to produce hepatotoxic effects, and liver problems are extremely unlikely with this compound.
It is also likely that Proviron may have a suppressive effect on endogenous natural Testosterone production though this is considered to be very weak. Nevertheless, studies have demonstrated that mg or less per day of Proviron that no significant suppression of Testosterone results.
In those same studies, higher dosages mg or higher per day resulted in significant suppression of Testosterone levels. In the medical world for the treatment of insufficient androgenicity, a single tablet of 25mg taken three times per day for a total of 75mg per day is used at the onset of treatment, followed by a reduction in dose later on to maintenance levels of a single 25mg tablet per day.
In the treatment of male infertility, the same dosages are normally used, though other fertility-boosting drugs are also included alongside Proviron. In the case of bodybuilders and athletes, Proviron is normally used between 50 — mg per day to either control Estrogen levels, reduce water retention caused by estrogen , or to increase fertility following the conclusion of a cycle. Although Proviron is not approved for use in females, some females in the athletic and bodybuilding community do elect to use it.
In this case, a single Proviron dosage of 25mg per day is enough to alter the look of the physique. This should be done no longer than 4 — 5 weeks in order to avoid virilization effects. Being that Proviron is not an anabolic steroid and possesses extremely weak anabolic effects, it is not utilized in the form of cycles. It is instead normally utilized as an ancillary compound, as an adjunct to anabolic steroid cycles in order to minimize or mitigate the effects of Estrogen on the body.
When used as an ancillary, it can be taken by male athletes and bodybuilders all throughout their cycle length at 50 — mg per day, as there is no limit to how long it can be utilized for. Although this can be done, there are much better compounds with similar and stronger effects for PCT. When the risk of even weak endogenous Testosterone suppression is thrown into the mix with Proviron, it is advised to avoid the use of Proviron for PCT purposes unless there are no other options available.
During a period in which individuals are attempting to recover their natural endogenous Testosterone levels, any threat no matter how minimal to endogenous Testosterone production should be unwelcome and avoided at all costs. Rules, regulations, and laws can vary a great deal between countries, regions, and areas of the world. Therefore, the three major Western countries where anabolic steroid use is most prevalent will be covered. An important note to make here is that although Proviron scientifically and by nature is not considered an anabolic steroid due to its complete lack of anabolic effects , it unfortunately has been legislated in some countries as an anabolic steroid due to its chemical structure, and is therefore legally treated as such.
Needless to say, trafficking, importation, and the purchase of Proviron or any anabolic steroid is a criminal act. Importing Proviron for personal use is also not a felony. In Canada, a similar law to that of the UK runs true where it is a Schedule IV drug, whereby possession and use of Proviron is not a felony and is legal.
However, trafficking of the substance is a felony. Proviron is nowhere near as popular on the market as other compounds, ancillaries, or anabolic steroids , but it is still regarded as somewhat of a staple item and should be easily located on most source lists of products available for sale. The vast majority of Mesterolone is produced by, or under license from Schering pharmaceuticals.
Because of the nature of Proviron, counterfeit or fake products have never been known as an issue, but everyone should still be aware of the risks involved with counterfeits of pharmaceutical products.
Aside from pharmaceutical grade products, there are underground lab UGL produced products. Proviron is known to be manufactured by some well-known underground labs, while lesser known or smaller UGLs may not manufacture it due to the fact that it is nowhere near as popular as other products or ancillaries out there. Drug Abuse Handbook, Second Edition.
Allahbadia; Rita Basuray Das 12 November Principles and Practice of Endocrinology and Metabolism. Newton 6 December Expert Opin Emerg Drugs. Elks 14 November The Dictionary of Drugs: Chemical Data, Structures and Bibliographies. National Association of Retail Druggists. Hall 6 December Concise Dictionary of Pharmacological Agents: Snyder; Shelly Rainforth Collins 5 August Pharmacology for Canadian Health Care Practice.
Methods Find Exp Clin Pharmacol. Androstanolone stanolone, dihydrotestosterone, DHT Androstanolone esters Bolazine capronate Drostanolone propionate dromostanolone propionate Epitiostanol Mepitiostane Mesterolone Metenolone acetate methenolone acetate Metenolone enanthate methenolone enanthate Stenbolone acetate Nortestosterone derivatives: Bolandiol dipropionate Nandrolone esters e.
Danazol Gestrinone Progestins e. D 2 receptor antagonists prolactin releasers e. Androvax androstenedione albumin Ovandrotone albumin Fecundin.
Retrieved from " https: Views Read Edit View history. This page was last edited on 19 December , at
Allahbadia; Rita Basuray Das 12 November It is an oral product, and is not considered an anabolic steroid.
Mesterolone is so old, in fact, that it shared its inception alongside Methyltestosterone in , and Testosterone Propionate in , which were two of the first anabolic steroids put to use in medicine as well. This page was last edited on 19 December , at From Basic to Clinical Aspects.
Because Mesterolone is not C alpha alkylated it is instead methylated on mesterolone first carbon mesteeolone research has shown that it is not known to produce hepatotoxic effects, meterolone liver problems are extremely unlikely with this compound. Pharmacology for Canadian Health Care Practice. Androstanolone stanolone, dihydrotestosterone, DHT Androstanolone esters Anadrol green giants capronate Drostanolone propionate dromostanolone propionate Epitiostanol Mepitiostane Mesterolone Metenolone acetate methenolone acetate Metenolone enanthate methenolone enanthate Stenbolone acetate Nortestosterone derivatives: Dan's educational emphasis mesterolone on mesterolone enhancement drugs PEDsendocrinology, nutritional supplements and strategies for health, fat reduction, anti-ageing, muscle growth, disease control and vaccinations. Side mesterolone of mesterolone include virilization among others.
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